We break down why they don't and offer tips for soothing cramps — regardless of what's causing them.The bottom line. Tampons don’t makecrampsworse and have nothing to do with them — period. Tampons & period cramps: Anecdotal evidence. The scientific answer is out of the way: Prostaglandins cause cramps, not tampons. But howdo we reconcile this with the many accounts from people with periods that tamponsdo, in fact, lead to cramping? Tampons can makecrampsworse due to tension in the vaginal muscles, absorbency mismatch, or sensitivity to materials. Learn how these factors impact comfort. Bala (she/her), ND, tampons can worsencramps for some people. It’s not always related, but for those with pelvic floor dysfunction, vaginismus, or other irritability in the vagina, tampons can create more pain. Cramping, bloating, and period poops (you know what we’re talking about) all require comfort and a period product that isn’t constantly threatening to pop out at even the smallest of sneezes. You might be wondering howtampons and cups can makecrampsworse. Why can tamponsmakecrampsworse for some people? Here’s the nuance, though. While tampons haven’t been shown to cause cramping, so many people swear that tampons impact the intensity of their pain. #1 Organic Tampons Are Better for the Environment.