Dotampons really make cramps worse? We break down why they don't and offer tips for soothing cramps — regardless of what's causing them.How to soothe cramps. Tampons may not be the cause of your cramps, but that doesn’t mean you can’t find relief. No, tamponsdo not make cramps worse, ob-gyn Sameena Rahman, MD, confirms. "Period cramps are due to contractions in the uterus," she says, and tamponsdo not come into contact with the uterus or have anything to do with the contractions that may come from the uterus. Tampons & period cramps: Anecdotal evidence. The scientific answer is out of the way: Prostaglandins cause cramps, not tampons. But how do we reconcile this with the many accounts from people with periods that tamponsdo, in fact, lead to cramping? Tampons can make cramps worse due to tension in the vaginal muscles, absorbency mismatch, or sensitivity to materials. Learn how these factors impact comfort. menstrualcramps vs tampon pain. Internal protection discomfort differs significantly from menstrual pain. Tampon-related sensations often feel like deep abdominal pressure. This differs from vaginal entrance discomfort during insertion. Normal menstrualcramps usually begin at the start of menstruation and last for a few hours to a day.